The thing I think could be interesting to watch will be the Skins secondary being tested by not only good receivers but a QB with an almost uncanny ability to hit them even when they're covered.
Maybe although our secondary has had an advantage all season long...a front four that can get pressure often without help from the blitz. Brees has not faced that much this season, at least not much when I have watched. NE was absolutely incapable of generating any pass rush without blitzing Monday night and NO feasted on that.
I really think this could be the toughest regular season test the NO offense has for the whole of it's 16 game regular schedule. I just don't see Brees having a perfect game, on the road in foul December DC weather, against the rush the Skins can bring with just Orakpo, Haynesworth, Griffin and Carter.